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Mel B. Feany, M.D.,Ph.D.
Associate Professor of Pathology
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Academic Activities:
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Office
77 Avenue Louis Pasteur
HNRB-0630F
Boston,MA
02115
Email1:
mfeany@partners.org
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Education and Training:
Medical School
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Albert Einstein College of Medicine
M.D.
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Graduate School
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Harvard University Graduate School of Arts And Sciences
Ph.D.
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Residency
7/1/95
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6/30/97
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Brigham and Women's Hospital
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Fellowship
7/1/1997
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6/30/1999
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Brigham and Women's Hospital
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Clinical Specialties:
Research Interests:
Publication:
- Feany MB, Quinn WG. A neuropeptide gene defined by the Drosophila memory mutant amnesiac. Science 1995; 268:869-873. (see also accompanying "Perspectives" in same issue)
- Feany MB, Dickson DW. Widespread cytoskeletal pathology characterizes corticobasal degeneration. Am J Pathol 1995; 146:1388-1396.
- Feany MB, Bender WW, A Drosophila model of Parkinson's disease. Nature 2000; 404:394-398. (see also accompanying "News and Views" in same issue).
- Wittmann CW, Wszolek MF, Shulman JM, Salvaterra PM, Lewis J, Hutton M, Feany MB. Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles. Science 2001 Jun 14 (epub ahead of print). See also accompanying News Article in same issue.
- Feany MB. Studying human neurodegenerative diseases in flies and worms. J Neuropathol Exptl Neurol 2000; 59:847-856.
- Chen L, Feany MB. a-synuclein phosphorylation controls neurotoxicity and inclusion formation in a Drosophila model of Parkinson disease. Nat Neurosci 2005;8:657-63.
- Khurana V, Lu Y, Steinhilb ML, Oldham S, Shulman JM, Feany MB. TOR-mediated cell-cycle activation causes neurodegeneration in a Drosophila tauopathy model. Curr Biol 2006;16:230-41.
- Dias-Santagata D, Fulga T, Duttaroy A, Feany MB. Oxidative stress mediates tau-induced neurodegeneration in Drosophila. J Clin Invest 2007;117:236-45.
- Fulga T, Elson-Schwab I, Khurana V, Steinhilb ML, Spires TL, Hyman BT, Feany MB. Abnormal bundling and accumulation of F-actin mediates tau-induced neuronal degeneration in vivo. Nat Cell Biol 2007;9:139-48.
- Periquet M, Fulga T, Myllykangas L, Schlossmacher MG, Feany MB. Aggregation of a-synuclein mediates neurotoxicity in vivo. J Neurosci 2007;27:3338-46.
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