Department of Pathology
  Brigham and Women's Hospital
  A teaching Affliate of Harvard Medical School
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Frank Chuan Kuo, M.D.,Ph.D.

Associate Professor of Pathology, Harvard Medical School
Director, Pathology Informatics
Director, Assay Development, Center for Advanced Molecular Diagnostics
Core Director, Pathology Specimen Locator, DF/HCC
Academic Activities:
Computer-aided decision support for pathology and Bioinformatic tools in molecular diagnosis
Office
5022 Shapiro Building
70 Francis Street
Boston,MA 02115
Email1: fkuo@partners.org
Education and Training:

Medical School - 1986 : National Taiwan University, Taiwan M.D.
Graduate School - : Rockefeller University Ph.D.
Internship 7/1/83 - 6/30/84 : National Taiwan University Hospital
Fellowship 7/1/90 - 12/31/90 : Rockefeller University
Residency/Fellowship 01/01/1991 - 3/30/1993 : Brigham and Women's Hospital
Fellowship 04/01/1993 - 10/31/1993 : Brigham and Women's Hospital
Fellowship 1994 - 1995 : Brigham and Women's Hospital

Clinical Specialties:
  • Anatomic Pathology
  • Hematopathology
  • Hematology
  • Molecular Genetics
Research Interests:
  • Leukemia
  • Mutation
  • Gene expression profiling
  • Cancer
  • Tumor angiogenesis
  • Cancer
Publication:
  1. Louis DN, Gerber GK, Baron JM, Bry L, Dighe AS, Getz G, Higgins JM, Kuo FC, Lane WJ, Michaelson JS, Le LP, Mermel CH, Gilbertson JR, Golden JA. Computational pathology: an emerging definition. Arch Pathol Lab Med. 2014 Sep;138(9):1133-8
  2. MacConaill LE, Garcia E, Shivdasani P, Ducar M, Adusumilli R, Breneiser M, Byrne M, Chung L, Conneely J, Crosby L, Garraway LA, Gong X, Hahn WC, Hatton C, Kantoff PW, Kluk M, Kuo F, Jia Y, Joshi R, Longtine J, Manning A, Palescandolo E, Sharaf N, Sholl L, van Hummelen P, Wade J, Wollinson BM, Zepf D, Rollins BJ, Lindeman NI. Prospective Enterprise-Level Molecular Genotyping of a Cohort of Cancer Patients. The Journal of Molecular Diagnostics 16:6, 660-672
  3. Field S, Tsai F-Y, Kuo FC, Zubiaga AM, Kaelin WG, Livingston DM, Orkin SH, Greenberg ME. E2F1 functions in mice to promote apoptosis and suppress proliferation. Cell 1996; 85:549-561
  4. Mandelker D, Lee RE, Platt MY, Riedlinger G, Quinn A, Rao LK, Klepeis VE, Mahowald M, Lane WJ, Beckwith BA, Baron JM, McClintock DS, Kuo FC, Lebo MS, Gilbertson JR. Pathology informatics fellowship training: Focus on molecular pathology. J Pathol Inform. 2014 Mar 28;5:11.
  5. Weigert O, Kopp N, Lane AA, Yoda A, Dahlberg SE, Neuberg D, Bahar AY, Chapuy B, Kutok JL, Longtine JA, Kuo FC, Haley T, Salois M, Sullivan TJ, Fisher DC, Fox EA, Rodig SJ, Antin JH, Weinstock DM. Molecular ontogeny of donor-derived follicular lymphomas occurring after hematopoietic cell transplantation. Cancer Discov. 2012 Jan;2(1):47-55.
  6. Badalian-Very B, Vergilio J, Degar B, MacConaill L, Brandner B, Calicchio M, Kuo FC, Azra H. Ligon, Stevenson K, Kehoe SM, Garraway LA, Hahn WC, Meyerson M, Fleming MD, and Rollins BJ Recurrent BRAF mutations in Langerhans cell histiocytosis Blood 2010 Jun 2. 116(11):1919-23
  7. Luo B, Aster JC, Hasserjian RP, Kuo F, Sklar J. Isolation and functional analysis of a cDNA for human Jagged2, a gene encoding a ligand for the Notch1 receptor. Mol & Cell Biol 1997; 17:6057-6067.
  8. Wang LC, Kuo F, Fujiwara Y, Gilliland DG, Golub TR, Orkin SH. Yolk sac angiogenic defect and intra-embryonic apoptosis in mice lacking the Ets-related factor TEL. Embo J 1997; 16:4374-4383
  9. Tsai F-Y, Keller G, Kuo FC, Weiss M, Chen J-C, Alt F, Orkin SH. An early hematopoietic defect in mice lacking the transcription factor GATA-2. Nature 1994; 371:221-226
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<Friday, October 20, 2017>
8:00 AM
Dr. Maria Kuba, Dr. Yi Daniel Li
Cotran Conference Center
9:15 AM

Autopsy suite
12:00 PM

GYN 14-headed scope
1:00 PM
Dr. Christopher Fletcher
Cotran Conference Center
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