Department of Pathology
  Brigham and Women's Hospital
  A teaching Affliate of Harvard Medical School
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Francis W. Luscinskas, Ph.D.

Associate Professor of Pathology, Harvard Medical School



Academic Activities:

Office
77 Avenue Louis Pasteur
HNRB-7-752p
Boston,MA 02115
Email1: fluscinskas@partners.org
Education and Training:

Graduate School - : Boston University School of Medicine Ph.D.
Professional Position 1/1/77 - 1/1/80 : St. Elizabeth's Hosp.,Blood Bank
Professional Position 1/1/78 - : Center for Disease Control & Prevention, Nat'l Center Ofor Env. Health

Clinical Specialties: Research Interests:
  • Endothelial cell biology
  • Atherosclerosis
Publication:
  1. Lim Y-C, Ding H, Snapp K, Kansas GS and Luscinskas FW. Contributions of PSGL-1 to monocyte initial attachment and subsequent accumulation on TNF-a activated endothelium under flow conditions in vitro. J. Immunol. 1998; 161:2501-2508.
  2. Gerzsten RA, Garcia-Zepeda E, Yoshida M, Ding H, Gimbrone MA, Luster A, Luscinskas FW, and Rosenzweig A. MCP-1 and IL-8 trigger firm adhesion of monocytes to vascular endothelium under laminar flow conditions. Nature. 1999; 398:718-723.
  3. Montoya MC, Borges E, Snapp KR, Holtmann K, Sánchez-Madrid F, Luscinskas FW, Kansas GS, Vestweber D, de Landázuri MO. Memory B lymphocytes from secondary lymphoid organs interact with E-selectin through a novel glycoprotein ligand. J Clin Invest 1999;103:1317-1327.
  4. Allport JR, Ding H, Muller WA, Luscinskas FW. Monocytes induce reversible flocal changes in VE-cadherin complex during transendothelial migration under flow. J Cell Biol 2000; 148:203-216.
  5. Lim Y-C, Xie H, Lichtman AH, Luscinskas FW. IL-12, STAT4 dependent upregulation of naïve T cell core 2 b-1,6-N-acetylglycosaminyltransferase (G2GnT), an enzyme essential for expression of functional selectin ligands. J Immunol 2001; in press.
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