Department of Pathology
  Brigham and Women's Hospital
  A teaching Affliate of Harvard Medical School
Login Skip Navigation Links
  Skip Navigation Links
HomeExpand Home





Announcement

Submit new announcement
Sabina Signoretti, M.D.

Associate Professor of Pathology, Harvard Medical School



Academic Activities:

Office
75 Francis Street
TH-5-504 Thorn Building
Boston,MA 02115
Email1: ssignoretti@partners.org
Website
Education and Training:

Medical School - : University of Rome "La Sapienza" M.D.
Residency 7/1/89 - 6/30/93 : University of Rome "La Sapienza"
Fellowship 7/1/96 - 12/31/96 : Beth Israel Hospital
Fellowship 1/1/97 - 6/30/98 : Beth Israel Hospital
Professional Position 7/1/98 - : Dana-Farber Cancer Institute
Professional Position 7/1/93 - 6/30/96 : Istituto Dermopatico Dell'immacolata

Clinical Specialties: Research Interests: Publication:
  1. Signoretti S, Montironi R Manola J, Altimari A, Tam C, Bubley G, Balk S, Thomas G, Kaplan I, Hlatky L, Hahnfeldt P, Kantoff P, Loda M. Her-2-neu expression and androgen independence in human prostate cancer. J Natl Cancer Inst 2000;92:1918-25.
  2. Signoretti S, Waltregny D, Dilks J, Isaac B, Lin D, Garraway L, Yang A, McKeon F, Montironi R, Loda M. p63 is a prostate basal cell marker and is required for prostate development. Am J Pathol 2000;157:1769-75.
  3. Waltregny D, Leav I, Signoretti S, Soung P, Lin D, Merk F, Adam YA, Bhattacharya N, Cirenei N, Loda M. Androgen-driven prostate epithelial cell proliferation and differentiation in vivo involve the regulation of p27 kip1 through its proteasome-mediated degradation. Mol Endocrinol 2001;15:765-82.
  4. Signoretti S, Loda M. Estrogen receptor beta in prostate cancer: brake pedal or accelerator? Am J Pathol 2001;159:13-6
  5. Signoretti S, di Marcotullio L, Richardson A, Ramaswamy S, Carrano A C, Isaac B, Rue M, Monti F, Loda M and Pagano M. Oncogenic role of the ubiquitin ligase subunit Skp2 in human breast cancer. J Clin Invest. 2002;110:633-4
  6. Bardeesy N, Sinha M, Hezel A F, Signoretti S, Hathaway N A, Sharpless N E, Loda M, Carrasco D R and DePinho RA. Loss of the Lkb1 tumor suppressor provokes intestinal polyposis but resistance to transformation. Nature. 2002;419:162-7.
  7. Graner E, Tang D, Rossi S, Baron A, Migita T, Weinstein LJ, Lechpammer M, Huesken D, Zimmermeann J, Signoretti S, Loda M. The isopeptidase USP2a regulates the stability of Fatty Acid Synthase in prostate cancer. Cancer Cell. 2004; 5:253-61
  8. Berger R, Febbo PG, Majumder PK, Zhao JJ, Mukherjee S, Signoretti S, Campbell KT, Sellers WR, Roberts TM, Loda M, Golub TR, Hahn WC. Androgen-induced differentiation and tumorigenicity of human prostate epithelial cells. Cancer Res. 2004; 64:8867-75
<December 2017>
SuMoTuWeThFrSa
262728293012
3456789
10111213141516
17181920212223
24252627282930
31123456


<Friday, December 15, 2017>
8:00 AM
Dr. Eleanor Russell-Goldman, Dr. Kristine Wong
Cotran Conference Center
9:15 AM

Autopsy suite
12:00 PM

GYN 14-headed scope
1:00 PM
Dr. Christopher Fletcher
Cotran Conference Center
Copyright 2008 - 2017, BWH Pathology, All rights reserved.