Department of Pathology
  Brigham and Women's Hospital
  A teaching Affliate of Harvard Medical School
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Tanya Mayadas-Norton, Ph.D.

Associate Professor of Pathology, Harvard Medical School

Academic Activities:

221 Longwood Ave.
EBRC 221L-404a
Boston,MA 02115
Education and Training:

Graduate School - : University of Rochester Ph.D.
Fellowship 12/1/89 - 12/31/92 : New England Medical Center - Tufts School of Medicine
Fellowship 12/1/90 - 12/31/92 : Massachusetts Institute Of Technology, Cancer Research Center

Clinical Specialties: Research Interests: Publication:
  1. Mayadas TN, Johnson RC, Rayburn H, Hynes RO, Wagner DD. Leukocyte rolling and extravasation are severely compromised in P-selectin-deficient mice. Cell 1993; 74:541-554
  2. Tang T, Frenette PS, Hynes RO, Wagner DD, Mayadas TN. Response to cytokine-induced meningitis is dramatically attenuated in mice deficient in endothelial selectins. J Clin Invest 1996; 97:2485-2490.
  3. Coxon A, Barkalow FJ, Askari S, Rieu P, Sharpe AH, von-Andrian UH, Arnaout MA, Mayadas TN. A novel role for the b2 integrin, CD11b/CD18, in neutrophil apoptosis: A homeostatic mechanism in inflammation. Immunity 1996; 5:653-666.
  4. Tang TT, Rosenkranz A, Assmann KJM, Goodman MJ, Gutierrez-Ramos J-C, Carroll MC, Cotran RS, Mayadas TN. A role for Mac-1 (CD11b/CD18) in FcgR interactions in vivo: Mac-1 deficiency abrogates sustained neutrophil adhesion and proteinuria in Fc-dependent anti-glomerular basement membrane nephritis. J Exp Med 1997; 186:1853-1863.
  5. Coxon A, Cullere X, Knight S, Sethi S, Wakelin MW, Stavrakis G, Luscinskas FW, Mayadas TN. Fc gamma RIII mediates neutrophil recruitment to immune complexes. a mechanism for neutrophil accumulation in immune-mediated inflammation.Immunity. 2001 Jun;14(6):693-704.
  6. Cullere X, Shaw SK, Andersson L, Hirahashi J, Luscinskas FW, Mayadas TN.Regulation of vascular endothelial barrier function by Epac, a cAMP-activated exchange factor for Rap GTPase. Blood. 2005 Mar 1;105(5):1950-5. Epub 2004 Sep 16.
  7. Vielhauer V, Stavrakis G, Mayadas TN. Renal cell-expressed TNF receptor 2, not receptor 1, is essential for the development of glomerulonephritis.J Clin Invest. 2005 May;115(5):1199-209.
  8. Cullere X, Lauterbach M, Tsuboi N, Mayadas TN. Neutrophil-selective CD18 silencing using RNA interference in vivo. Blood. 2008 Apr 1;111(7):3591-8.
  9. Sehrawat S, Cullere X, Patel S, Italiano J Jr, Mayadas TN. Role of epac1, an exchange factor for rap GTPases, in endothelial microtubule dynamics and barrier function. Mol Biol Cell. 2008 Mar;19(3):1261-70
  10. Tsuboi N, Asano K, Lauterbach M, Mayadas TN. Human neutrophil Fcgamma receptors initiate and play specialized nonredundant roles in antibody-mediated inflammatory diseases. Immunity. 2008 Jun;28(6):833-46.
<June 2019>

<Monday, June 24, 2019>
8:00 AM

Cotran Conference Center
8:00 AM

Autopsy suite
9:00 AM

Clinical Lab conference room
3:00 PM

Dammin signout suite
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