Department of Pathology
  Brigham and Women's Hospital
  A teaching Affliate of Harvard Medical School
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Inga-Marie Schaefer, M.D.

Clinical Fellow
Translational sarcoma research, Anatomic pathology, Soft tissue and bone pathology, Molecular pathology
75 Francis Street
Amory 3
Boston, MA 02115
Education and Training:
  • Medical school - Georg-August University Goettingen, Germany, 2003-2009
  • Doctoral thesis (M.D.) - University Bern, Switzerland, 2007-2009
  • Residency, Anatomic Pathology - University Medical Center Goettingen, Germany, 2010-2013
BWH Pathology tenure:
  • AP Chief Resident : 07/01/2017 - 09/30/2017
  • PGY-2 : 07/01/2016 - 06/30/2017
  • PGY-1 : 07/01/2015 - 06/30/2016
  • Research Fellow : 07/01/2013 - 06/30/2015
  1. What is New in Gastrointestinal Stromal Tumor? Schaefer IM, Mariño-Enríquez A, Fletcher JA. Adv Anat Pathol. 2017 Jun 19.
  2. Histologic Appearance After Preoperative Radiation Therapy for Soft Tissue Sarcoma: Assessment of the European Organization for Research and Treatment of Cancer-Soft Tissue and Bone Sarcoma Group Response Score. Schaefer IM, Hornick JL, Barysauskas CM, Raut CP, Patel SA, Royce TJ, Fletcher CDM, Baldini EH. Int J Radiat Oncol Biol Phys. 2017 Jun 1;98(2):375-383.
  3. Sarcomas With CIC-rearrangements Are a Distinct Pathologic Entity With Aggressive Outcome: A Clinicopathologic and Molecular Study of 115 Cases. Antonescu CR1, Owosho AA, Zhang L, Chen S, Deniz K, Huryn JM, Kao YC, Huang SC, Singer S, Tap W, Schaefer IM, Fletcher CD. Am J Surg Pathol. 2017 Jul;41(7):941-949.
  4. MAX inactivation is an early event in GIST development that regulates p16 and cell proliferation. Schaefer IM, Wang Y, Liang CW, Bahri N, Quattrone A, Doyle L, Mariño-Enríquez A, Lauria A, Zhu M, Debiec-Rychter M, Grunewald S, Hechtman JF, Dufresne A, Antonescu CR, Beadling C, Sicinska ET, van de Rijn M, Demetri GD, Ladanyi M, Corless CL, Heinrich MC, Raut CP, Bauer S, Fletcher JA. Nat Commun. 2017 Mar 8;8:14674.
  5. Abnormal p53 and p16 staining patterns distinguish uterine leiomyosarcoma from inflammatory myofibroblastic tumour. Schaefer IM, Hornick JL, Sholl LM, Quade BJ, Nucci MR, Parra-Herran C. Histopathology. 2017 Jun;70(7):1138-1146.
  6. Claudin-4 expression distinguishes SWI/SNF complex-deficient undifferentiated carcinomas from sarcomas. Schaefer IM, Agaimy A, Fletcher CD, Hornick JL. Mod Pathol. 2017 Apr;30(4):539-548.
  7. Myolipoma of Soft Tissue: Clinicopathologic Analysis of 34 Cases. Fukushima M, Schaefer IM, Fletcher CD.Am J Surg Pathol. 2017 Feb;41(2):153-160.
  8. TERT promoter mutations and prognosis in solitary fibrous tumor. Bahrami A, Lee S, Schaefer IM, Boland JM, Patton KT, Pounds S, Fletcher CD. Mod Pathol. 2016 Dec;29(12):1511-1522.
  9. H3K27me3 immunohistochemistry highlights the inactivated X chromosome (Xi) and predicts sex in non-neoplastic tissues. Schaefer IM, Minkovsky A, Hornick JL. Histopathology. 2016 Mar 22.
  10. Loss of H3K27 trimethylation distinguishes malignant peripheral nerve sheath tumors from histologic mimics. Schaefer IM, Fletcher CD, Hornick JL. Mod Pathol. 2015 Nov 20.
  11. Diagnostically Challenging Spindle Cell Neoplasms of the Retroperitoneum. Schaefer IM, Fletcher CD. Surg Pathol Clin. 2015 Sep;8(3):353-74.
  12. Chromosomal aberrations in primary PDGFRA-mutated gastrointestinal stromal tumors. Schaefer IM, Delfs C, Cameron S, Gunawan B, Agaimy A, Ghadimi BM, Haller F. Hum Pathol. 2014 Jan;45(1):85-97.
  13. Malignant peripheral nerve sheath tumor (MPNST) arising in diffuse-type neurofibroma: clinicopathologic characterization in a series of 9 cases. Schaefer IM, Fletcher CD. Am J Surg Pathol. 2015 Sep;39(9):1234-41.
  14. Combined DNA methylation and gene expression profiling in gastrointestinal stromal tumors reveals hypomethylation of SPP1 as an independent prognostic factor. Haller F, Zhang JD, Moskalev EA, Braun A, Otto C, Geddert H, Riazalhosseini Y, Ward A, Balwierz A, Schaefer IM, Cameron S, Ghadimi BM, Agaimy A, Fletcher JA, Hoheisel J, Hartmann A, Werner M, Wiemann S, Sahin O. Int J Cancer. 2015 Mar 1;136(5):1013-23.
  15. Aberrant DNA hypermethylation of SDHC: a novel mechanism of tumor development in Carney triad. Haller F, Moskalev EA, Faucz FR, Barthelmeß S, Wiemann S, Bieg M, Assie G, Bertherat J, Schaefer IM, Otto C, Rattenberry E, Maher ER, Ströbel P, Werner M, Carney JA, Hartmann A, Stratakis CA, Agaimy A. Endocr Relat Cancer. 2014 Aug;21(4):567-77.
  16. Uniparental Trisomy of a Mutated HRAS Proto-Oncogene in Embryonal Rhabdomyosarcoma of a Patient With Costello Syndrome. Menke J, Pauli S, Sigler M, Kühnle I, Shoukier M, Zoll B, Ganster C, Salinas-Riester G, Schaefer IM. J Clin Oncol. 2015 May 1;33(13):e62-5.
  17. Rhabdoid morphology in gastrointestinal stromal tumours (GISTs) is associated with PDGFRA mutations but does not imply aggressive behaviour. Schaefer IM, Ströbel P, Cameron S, Beham A, Otto C, Schildhaus HU, Agaimy A. Histopathology. 2014 Feb;64(3):421-30.
  18. Myxoid variant of so-called angiomatoid "malignant fibrous histiocytoma": clinicopathologic characterization in a series of 21 cases. Schaefer IM, Fletcher CD. Am J Surg Pathol. 2014 Jun;38(6):816-23.
<May 2018>

<Wednesday, May 23, 2018>
8:00 AM

Autopsy suite
8:00 AM

Abrams conference room
11:00 AM

GYN 14-headed scope
1:00 PM
Dr. Christopher Crum, MD
Cotran Conference Center
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