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  Brigham and Women's Hospital
  A teaching Affliate of Harvard Medical School
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Matthew F. Rose, M.D., Ph.D.

Neuropathology Fellow
Neurodevelopmental Disorders
Office
75 Francis Street
AL3-117 Amory Building
Boston, MA 02115
Email1: mfrose@partners.org
Education and Training:
  • B.S. - University of Virginia, 2000
  • M.D. and Ph.D. - Baylor College of Medicine, 2009
  • Neurobiology Fellow - Marine Biological Laboratory, 2003
BWH Pathology tenure:
  • Neuropathology Fellow : 07/01/2012 - 06/30/2014
  • PGY-2 : 07/01/2011 - 06/30/2012
  • PGY-1 : 07/01/2010 - 06/30/2011
Publication:
  1. Carroll Driver E, Sillers L, Coate TM, Rose MF, Kelley MW. (2013). The Atoh1-lineage gives rise to hair cells and supporting cells within the mammalian cochlea. Developmental Biology. [Epub ahead of print]
  2. Rose MF, Ahmad KA, Thaller C, Zoghbi HY. (2009). Excitatory neurons of the proprioceptive, interoceptive, and arousal hindbrain networks share a developmental requirement for Math1. Proceedings of the National Academy of Sciences, USA. 106(52):22462-7.
  3. Rose MF, Ren J, Ahmad KA, Chao HT, Klisch TJ, Flora A, Greer JJ, Zoghbi HY. (2009). Math1 is essential for the development of hindbrain neurons critical for perinatal breathing. Neuron. 12;64(3):341-54.
  4. Englund C, Kowalczyk T, Daza RA, Dagan A, Lau C, Rose MF, Hevner RF. (2006). Unipolar brush cells of the cerebellum are produced in the rhombic lip and migrate through developing white matter. Journal of Neuroscience. 26(36):9184-95.
  5. Chizhikov VV, Lindgren AG, Currle DS, Rose MF, Monuki ES, Millen KJ. (2006). The roof plate regulates cerebellar cell-type specification and proliferation. Development. 133(15):2793-804.
  6. Young JI, Hong EP, Castle JC, Crespo-Barreto J, Bowman AB, Rose MF, Kang D, Richman R, Johnson JM, Berget S, Zoghbi HY. (2005). Regulation of RNA splicing by the methylation-dependent transcriptional repressor methyl-CpG binding protein 2. Proceedings of the National Academy of Sciences, USA. 102(49):17551-8.
  7. Wang VY*, Rose MF*, Zoghbi HY. (2005). Math1 expression redefines the rhombic lip derivatives and reveals novel lineages within the brainstem and cerebellum. Neuron. 48(1):31-43. (* equal contribution)
  8. Tsuda H, Jafar-Nejad H, Patel AJ, Sun Y, Chen HK, Rose MF, Venken KJ, Botas J, Orr HT, Bellen HJ, Zoghbi HY. (2005). The AXH domain of Ataxin-1 mediates neurodegeneration through its interaction with Gfi-1/Senseless proteins. Cell. 122(4):633-44.
  9. Frankfort BJ, Pepple KL, Mamlouk M, Rose MF, Mardon G. (2004). Senseless is required for pupal retinal development in Drosophila. Genesis. 38(4):182-94.
  10. Rose MF, Rose SR. (1998) Melatonin accelerates metamorphosis in Xenopus laevis. Journal of Pineal Research. 24(2):90-5.
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