Department of Pathology
  Brigham and Women's Hospital
  A teaching Affliate of Harvard Medical School
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Lynette Marie Sholl, M.D.

   Instructor in Pathology
Academic Activities:
Molecular mechanisms of pulmonary tumorigenesis
Office
75 Francis Street
AL3-107 Amory Building
Boston,MA 02115
Email1: lmsholl@partners.org
Education and Training:

Medical School - : Stanford University School of Medicine M.D
Internship 06/2003 - 06/2004 : Hospital of the University of Pennsylvania internship
Residency 2004 - 2008 : Brigham and Women's Hospital
Fellowship 2006 - 2007 : Molecular Genetic Pathology
Fellowship 2008 - 2009 : Brigham and Women's Hospital Corson Thoracic Pathology Fellowship

Clinical Specialties:
  • Anatomic Pathology
  • Molecular Diagnostics
  • Pulmonary Pathology
Research Interests: Publication:
  1. Validation of chromogenic in situ hybridization for detection of EGFR copy number amplification in nonsmall cell lung carcinoma.
  2. Lung Adenocarcinoma with EGFR Amplification Has Distinct Clinicopathologic and Molecular Features in Never-Smokers.
  3. Sox2 Expression in Pulmonary Non-small Cell and Neuroendocrine Carcinomas.
  4. Clinical JAK2V617F mutation testing: Limited utility for general hospital patients with venous and arterial thromboses in common locations.
  5. Maternal Par4 and platelets contribute to defective placenta formation in mouse embryos lacking thrombomodulin.
  6. Immunohistochemical analysis of langerin in langerhans cell histiocytosis and pulmonary inflammatory and infectious diseases.
  7. Mutation-specific antibodies for the detection of EGFR mutations in non-small-cell lung cancer.
  8. In situ genetic analysis of cellular chimerism.
  9. Preferential activation of nuclear factor of activated T cells c correlates with mouse strain susceptibility to allergic responses and interleukin-4 gene expression.
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