Department of Pathology
  Brigham and Women's Hospital
  A teaching Affliate of Harvard Medical School
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Mel B. Feany, M.D.,Ph.D.

Associate Professor of Pathology, Harvard Medical School

Academic Activities:

77 Avenue Louis Pasteur
Boston,MA 02115
Education and Training:

Medical School - : Albert Einstein College of Medicine M.D.
Graduate School - : Harvard University Graduate School of Arts And Sciences Ph.D.
Residency 7/1/95 - 6/30/97 : Brigham and Women's Hospital
Fellowship 7/1/1997 - 6/30/1999 : Brigham and Women's Hospital

Clinical Specialties:
  • Neuropathology
Research Interests:
  • Neurobiology
  1. Feany MB, Quinn WG. A neuropeptide gene defined by the Drosophila memory mutant amnesiac. Science 1995; 268:869-873. (see also accompanying "Perspectives" in same issue)
  2. Feany MB, Dickson DW. Widespread cytoskeletal pathology characterizes corticobasal degeneration. Am J Pathol 1995; 146:1388-1396.
  3. Feany MB, Bender WW, A Drosophila model of Parkinson's disease. Nature 2000; 404:394-398. (see also accompanying "News and Views" in same issue).
  4. Wittmann CW, Wszolek MF, Shulman JM, Salvaterra PM, Lewis J, Hutton M, Feany MB. Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles. Science 2001 Jun 14 (epub ahead of print). See also accompanying News Article in same issue.
  5. Feany MB. Studying human neurodegenerative diseases in flies and worms. J Neuropathol Exptl Neurol 2000; 59:847-856.
  6. Chen L, Feany MB. a-synuclein phosphorylation controls neurotoxicity and inclusion formation in a Drosophila model of Parkinson disease. Nat Neurosci 2005;8:657-63.
  7. Khurana V, Lu Y, Steinhilb ML, Oldham S, Shulman JM, Feany MB. TOR-mediated cell-cycle activation causes neurodegeneration in a Drosophila tauopathy model. Curr Biol 2006;16:230-41.
  8. Dias-Santagata D, Fulga T, Duttaroy A, Feany MB. Oxidative stress mediates tau-induced neurodegeneration in Drosophila. J Clin Invest 2007;117:236-45.
  9. Fulga T, Elson-Schwab I, Khurana V, Steinhilb ML, Spires TL, Hyman BT, Feany MB. Abnormal bundling and accumulation of F-actin mediates tau-induced neuronal degeneration in vivo. Nat Cell Biol 2007;9:139-48.
  10. Periquet M, Fulga T, Myllykangas L, Schlossmacher MG, Feany MB. Aggregation of a-synuclein mediates neurotoxicity in vivo. J Neurosci 2007;27:3338-46.
<September 2019>

<Sunday, September 15, 2019>
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