Department of Pathology
  Brigham and Women's Hospital
  A teaching Affliate of Harvard Medical School
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Ruben D. Carrasco, M.D.,Ph.D.

Instructor in Pathology, Harvard Medical School



Academic Activities:

Office
44 Brookline Ave.
D530
Boston,MA 02115
Email1: ruben_carrasco@dfci.harvard.edu
Education and Training:

Medical School - : Universidad De Chile, Chile M.D.
Graduate School - : University of Chile Ph.D.
Internship 1/1/80 - 12/31/82 : Barros Lucos Trudeau
Residency 7/1/97 - 6/30/99 : Massachusetts General Hospital
Residency 1/1983 - 12/1986 : Barros Lucos Trudeau

Clinical Specialties:
  • Hematopathology
  • Anatomic Pathology
Research Interests:
  • Myeloma
  • Oncogenesis
  • Signalling pathway
  • Mouse models
Publication:
  1. Tassone P, Neri P, Carrasco DR, Burger R, Goldmacher VS, Fram R, Munshi V, Shammas MA, Catley L, Jacob GS, Venuta S, Anderson KC, Munshi NC. A clinically relevant SCID-hu in vivo model of human multiple myeloma. Blood 2005;106:713-6.
  2. Munshi NC, Hideshima T, Carrasco D, Shammas M, Auclair D, Davies F, Mitsiades N, Mitsiades C, Kim RS, Li C, Rajkumar SV, Fonseca R, Bergsagel L, Chauhan D, Anderson KC. Identification of genes modulated in multiple myeloma using genetically identical twin samples. Blood 2004;103:1799-806.
  3. Tassone P, Goldmacher VS, Neri P, Gozzini A, Shammas MA, Whiteman KR, Hylander-Gans LL, Carrasco DR, Hideshima T, Shringarpure R, Shi J, Allam CK, Wijdenes J, Venuta S, Munshi NC, Anderson KC. Cytotoxic activity of the maytansinoid immunoconjugate B-B4-DM1 against CD138+ multiple myeloma cells. Blood 2004;104:3688-96.
  4. Tassone P, Gozzini A, Goldmacher V, Shammas MA, Whiteman KR, Carrasco DR, Li C, Allam CK, Venuta S, Anderson KC, Munshi NC. In vitro and in vivo activity of the maytansinoid immunoconjugate huN901-DM1 against CD56+ multiple myeloma cells. Cancer Res 2004;64:4629-36.
  5. Wong KK, Maser RS, Bachoo RM, Menon J, Carrasco DR, Gu Y, Alt FW, DePinho RA. Telomere dysfunction and Atm deficiency compromises organ homeostasis and accelerates ageing. Nature 2003;421:643-8.
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