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Scott J. Rodig, M.D.,Ph.D.
Assistant Professor of Pathology
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Academic Activities:
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Office
75 Francis Street
TH Thorn Building
Boston,MA
02115
Email1:
sjrodig@partners.org
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Education and Training:
Medical School
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Washington University School of Medicine
M.D.,Ph.D.
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Residency
7/1/98
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Brigham and Women's Hospital
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Clinical Specialties:
- Hematopathology
- Hematology
- Molecular Diagnostics
Research Interests:
Publication:
- Meraz MA, White JM, Sheehan KCF, Bach EA, Rodig, SJ, Dighe AS, Kaplan DH, Riley JK, Greenlund AC, Cambell D, Carver-Moore K, DuBois RN, Clark R, Aguet M, Schreiber RD. Targeted disruption of the STAT1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway. Cell 1996; 84: 431-442.
- Rodig SJ, Meraz MA, White JM, Lampe PA, Riley JK, Arthur CA, King KL, Sheehan KCF, Yin L, Pennica D, Johnson EM, Schreiber RD. Disruption of the JAK1 gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses. Cell 1998; 93: 373-383.
- Migone TS, Rodig SJ, Cacalano NA, Berg M, Schreiber RD, Leonard WJ. Functional cooperation of the interleukin-2 receptor beta chain and Jak1 in phosphatidylinositol 3-kinase recruitment and phosphorylation. Mol Cell Bio. 1998; 18 (11): 6416-22.
- Satoskar AR, Rodig S, Telford III SR, Satoskar AA, Ghosh SK, von Lichtenberg F, David JR. IL-12 gene-deficient C57BL/6 mice are susceptible to Leishmania donovani but have diminished hepatic immunopathology. Eur J Immun. 2000; 30:834-839.
- Hu J, Roy SK, Shapiro PS, Rodig SR, Reddy SP, Platanias LC, Schreiber RD, Kalvakolanu DV. ERK1 and ERK2 activate CCAAAT/enhancer-binding protein-beta-dependent gene transcription in response to interferon-gamma. J Biol Chem, 2001;276(1):287-97.
- Rodig SJ, Jones D, Shahsafaei A, Dorfman DM. CCR6 is a functional chemokine receptor that serves to identify select B-cell non-Hodgkin's lymphomas. Hum Path, 2002; 33(12):1227-33.
- Rodig SJ, Savage KJ, Nguyen V, Pinkus GS, Shipp MA, Aster JC, Kutok JL. TRAF-1 expression and c-Rel activation distinguish classical Hodgkin lymphoma from other morphologically or immunophenotypically similar forms of malignant lymphoma. Am J Surg Path, 2005; 29(2):196-203.
- Rodig SJ, Shahsafaei A, Dorfman DM. The CD45 isoform B220 identifies select subsets of human B cells and B cell lymphoproliferative disorders. Hum Path, 2005; 36(1):51-7.
- Rodig SJ, Shahsafaei A, Li B, Mackay CR, Dorfman DM. BAFF-R, the major B cell activating factor receptor, is expressed on the majority of mature B cells and B cell lymphoproliferative disorders. Human Pathol, 2005; 36(10):1113-9.
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